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Phenylpropanolamine for Dogs

Phenylpropanolamine (brand names: Proin®, Propalin®, Cystolamine®, Uricon®, Uriflex-PT®) is a sympathomimetic medication used to deal with urinary incontinence because of bad muscle tone within the urethral sphincter. Its use in cats and puppies at certain doses to treat urinary incontinence is ‘off label’ or ‘greater label’.

The maximum normally said facet effects have been vomiting, loss of appetite, diarrhea, excessive salivation, agitation, tiredness, vocalization, confusion, expanded water intake, weight loss, weak spot, fever, panting, and reversible changes in pores and skin color (a flushing or shiny pink).

If your pooch is having issues with urinary incontinence or nasal congestion, your vet may prescribe phenylpropanolamine for her. Phenylpropanolamine is the active ingredient in several brand name medications for dogs, including Proin, PPA-RD, Cystolamine, and Propalin. While most pups generally tolerate this medication pretty well, it’s not without side effects, most of which usually are mild.

Phenylpropanolamine side consequences for your Pooch
Phenylpropanolamine is a medication you give your dog orally, either in tablet or liquid form, as directed by your vet. After taking the medicine, your pooch might experience some gastrointestinal upset and loose stools. She could become restless, irritable, or possibly aggressive. Her blood pressure or heart rate may increase. She might lose her appetite, experience urine retention, or develop tremors when taking the medication. If you notice any of these side effects, discuss them with your vet, who may stop the medication or adjust its dosage, depending on the severity of your pup’s symptoms.

Unusual reactions and drug interactions
Some dogs may have an allergic reaction to phenylpropanolamine, and symptoms such as facial swelling, excessive vomiting, hives, and cramps appear. Your dog can go into a coma. These effects are not normal. If you notice this, you will need to contact your vet immediately. This drug can interact negatively with other medications including non-steroidal anti-inflammatory drugs, ephedrine, epinephrine, beta-blockers, monoamine oxidase inhibitors, and tricyclic antidepressants. Talk to your veterinarian if your dog is taking any medications, including vitamins, and if your puppy is pregnant or breastfeeding before starting phenylpropanolamine.