Some potent human formulations can be used in the dog (e.g., clobetasol propionate); most of the veterinary formulations contain less potent agents. Tachyphylaxis, atrophy, and microbial infections can occur in cases of overuse.
Veterinarians use clobetasol propionate regularly to treat dogs. Clobetasol propionate is a highly effective synthetic corticosteroid available as a gel, spray, moisturizer, foaming, and cream, and a 0.05% cream is available as an over-the-counter treatment for skin disorders in animals (see reference 1, see reference 2). When used on the advice of a licensed veterinarian, clobetasol cream is a safe and effective way to heal irritated dog skin (see reference 2).
As the FDA drug label describes, propionate cream is absorbed through the skin, relieving itching, and pain when applied to the problem patch. As an immunosuppressant or a medication that limits the body’s immune response, it also reduces inflammation and redness, calming the skin and allowing it to heal (Reference 4).
First, use an Elizabethan collar to prevent your dog from reaching the lesion. Find one at any chain pet store; the cheaper plastic ones are just as effective as more expensive inflatable styles. Then, according to administration instructions from the pharmaceutical label, gently apply a thin layer of cream onto the rash, twice daily, until completely absorbed. Stop use when the rash has healed, and do not apply the cream for more than two weeks (Reference 4).
According to the FDA pharmaceutical label, you should not cover the rash; this can further increase the potency of the drug (Reference 4). If the skin lesion fails to heal or worsens, contact your veterinarian; your dog could have a more serious condition.
Stinging, burning, and itching are the most frequent side effects of treatment, according to the FDA (See Reference 4). In rare cases, according to the Clobetasol Side Effects page on Doctor Hanen Abdel Rahman, allergic reactions can occur. If your dog has difficulty breathing or a swollen face after using the cream, bring them to the nearest vet hospital immediately, as this indicates a serious allergic reaction (See Reference 5).
Can I use clobetasol propionate on my face?
How to use Clobetasol propionate Gel. Use this medication on the skin only. Do not use it on the face, groin, or underarms unless directed to do so by your doctor. … Apply a thin film of medication to the affected area and gently rub in, usually 2 times daily or as directed by your doctor.